Go back to the enewsletter W Hotels Worldwide has


first_imgGo back to the enewsletterW Hotels Worldwide has this week opened W Dubai – The Palm, located on the Palm Jumeirah, Dubai.W Dubai – The Palm is the newest W Escape, the W brand’s playful spin on the traditional resort experience and is set to add a new beat to the already dynamic and pulsating city. With its electrifying style, evocative design and eclectic destination restaurants led by world-class chefs including Massimo Bottura and Akira Back, W Dubai – The Palm will shine bright in the City of Gold.All 350 guestrooms and suites offer uninterrupted views and dreamy amenities. Curved walls are intricately tiled to glisten like the lights and colours of the sea at various times of the day, bringing the shoreline into each room. Modern graffiti adorns the walls of every room, featuring lyrics in Arabic from a popular song by Lebanese singer, Fairouz.After checking in, guests can check out the incredible amenities of W Dubai – The Palm, including the hotel’s multiple pools that sit in a wave-like pattern in the centre of the Escape to form the W brand’s WET Deck experience directly facing a fabulous beach with views of the Dubai skyline.The W brand’s signature AWAY Spa invites guests to ‘Stroll in and Strut out’, offering 10 treatment rooms, a steam room, sauna, experiential showers, a hammam and a couples’ suite. Guests are treated to a design inspired by the underwater perspective of a pearl diver, where iridescent shells reflect the sunlight that peeks through the ocean above. Relaxing, social and surreal, the space also features a Beauty Bar for touch-ups and ‘Quick Fix’ treatments. Guests can sweat it out at FIT (gym) which boasts state-of-the-art equipment overlooking the WET Deck, beach and skyline views, featuring abstract art inspired by the graceful forms of both jellyfish and the parachutes of adventure-seeking skydivers.W Dubai – The Palm features six beverage and food destinations. Translated as “I will be right back”, Torno Subito is the first restaurant outside of Italy by global culinary genius, chef Massimo Bottura, whose Osteria Francescana has been feted as the “World’s Best Restaurant”.Pro snowboarder turned adrenaline-fuelled culinary master, chef Akira Back, brings his modern taste of Japanese cuisine prepared with a Korean essence to the Middle East for the first time at Akira Back.SoBe (short for South Beach) is an adults-only playground inspired by the eclectic and vibrant spirit of Miami. This is the only rooftop bar in Dubai where guests can watch the sun sink into the Arabian Sea with 360-degree views to watch as the Dubai skyline lights up each night. Serving up eclectic live DJ performances, imaginative cocktails and even tattoo artists, there will be nothing else like it in the city.LIV offers guests greener, lighter, fresher and brighter options for breakfast, lunch and dinner and was designed using only upcycled materials, meaning no new materials were created to build the venue.“We are excited to bring the W brand to Palm Jumeirah with the highly anticipated opening of W Dubai – The Palm,” said Alex Kyriakidis, President and Managing Director, Middle East and Africa, Marriott International. “As our first W Escape in the region, W Dubai – The Palm combines the city’s unique allure with the brand’s bold design and dynamic lifestyle and gives it a locally relevant twist. With game-changing style, amplified entertainment and innovative culinary offerings, this W Escape will inject a fresh vibe into the local hospitality scene and offer the most sought-after luxury getaway for locals as well as global jet-setters.”More at www.wdubaithepalm.comGo back to the enewsletterlast_img read more

Gary Alfonso Fox Networks Group has hired a former


first_imgGary AlfonsoFox Networks Group has hired a former senior CNBC executive to become general manager of a restructured African operation.Gary Alfonso will lead FNG Africa,taking control of sub-Sahara operations for the broadcast group and sister business National Geographic Partners.In Africa, FNG operates pay TV networks Fox, FX, FoxCrime, Fox Sports, National Geographic, Nat Geo Wild, Nat Geo Gold and BabyTV.Nami Patel and Makhosazana Khanyile have also landed senior roles in a rejigged FNG operation, Patel is promoted from VP, business development, Europe and Africa, to CFO, UK and Africa, while FNG Africa marketing head Khanyile has been named director of sales and marketing.New chief Alfonso has worked in broadcasting for almost three decades. He joins from Nigeria-based broadcaster Gotel Communications, where he was COO, and was previously managing director of CNBC Africa and GM of Summit TV.“Our genre defining brands are market leaders in Africa, delivering year on year growth over the past three years,” said Adam Theiler, FNG’s executive VP, Nordics, Turkey, Greece, Israel and Africa.“Gary’s 29 years of leading industry experience will continue to drive our success, evolving our businesses to meet the changing media landscape as we bring the best in entertainment, factual and sports programming to audiences across the continent.”Alfonso, who will report to Theiler, said: “Working with the highly talented team in the FNG Africa office, I look forward to helping the business increase its regional footprint, in a challenging and dynamic media environment.”The news comes soon after Theiler tweaked FNG management in Turkey, promoting Cenk Soner and Mehmet Icagasioglu to new top-level positions.It is also the latest change at FNG Europe and Africa, which came into being in January with the 21st Century Fox-owned networks business dropped its Fox International Channels moniker and said goodbye to long-serving international chief Hernan Lopez in the process.last_img read more

Amos17 Israeli satellite operatorSpacecoms lates


first_imgAmos-17Israeli satellite operatorSpacecom’s latest satellite, Amos-17, is completing the final stages of its pre-launch preparation ahead of take-off later this summer for the 17°East orbital position.Amos-17 has beendesigned to targetthe African market. The craft’s C-band,Ka-band and Ku-bandcapacity will enable ti to provide broad regional beams and high throughput spot beams across Africa.Equipped with a digital payload from Boeing Satellite Systems International, the satellite has now completed its environmental testing simulating the launch and harsh space environment.Amos-17 is currently undergoing final preparation operations ahead of shipment to Cape Canaveral, where it is scheduled to be launched on a Falcon-9 launch vehicle by SpaceX.David Pollack, president and CEO of Spacecom said, “We are excited by the opportunities Amos-17 will offer our clients throughout Sub-Saharan Africa. With a state-of-the-art digital payload, it will be the most technologically advanced satellite to service Africa and will deliver a large variety of services as well as connect Africa, Europe and the Middle East. We have worked closely with the Boeing team and are very much looking forward to moving ahead in Africa.”last_img read more

John Garland Graves was taken aback when he walked


first_imgJohn Garland Graves was taken aback when he walked into his McKinleyville, Calif., gym in October and learned that his SilverSneakers membership was being canceled.Since 2014, Graves, 69, has enjoyed free access to the gym through SilverSneakers, the nation’s best-known fitness program for seniors. He was disturbed by the news, as are many other people who have recently learned they’re losing this benefit.A controversial business decision by UnitedHealthcare, the nation’s largest health insurance carrier, is causing the disruption. As of Jan. 1, the company is dropping SilverSneakers — an optional benefit — for 1.2 million customers with Medicare Advantage plans in 11 states (California, Connecticut, Illinois, Indiana, Iowa, Kansas, Missouri, Nebraska, Nevada, North Carolina and Utah) as well as 1.3 million customers with Medicare supplemental (Medigap) insurance in nine states (Arizona, California, Connecticut, Illinois, Indiana, North Carolina, Ohio, Utah and Wisconsin).Graves, who works out four to five days a week and has a UnitedHealthcare Medigap policy, decided to seek coverage elsewhere after the company raised his policy’s rates and eliminated SilverSneakers in California. He has signed up for a new policy with Blue Shield of California.Starting next year, UnitedHealthcare will offer members a package of fitness and wellness benefits instead of paying to use SilverSneakers — a move that will give the company more control over its benefits and may save it money.Seniors with UnitedHealthcare Medicare supplemental policies will get 50 percent off memberships at thousands of gyms across the country, telephone access to wellness coaches and access to various online communities and health-related resources.Those with Medicare Advantage policies can join Renew Active, UnitedHealthcare’s fitness program, with a network of more than 7,000 sites, at no cost, and qualify for an evaluation from a personal trainer and an online brain-training program, among other services.Steve Warner, who leads UnitedHealthcare’s Medicare Advantage product team, explained the company’s move by noting that over 90 percent of policyholders who are eligible for SilverSneakers “never step foot in a gym” or use this benefit.UnitedHealthcare wants to reach “a broader portion of our membership” with a “wider variety of fitness resources,” he said, noting that the company’s shift away from SilverSneakers began last year and has accelerated this year.Altogether, more than 5 million customers have been affected. But the company is making market-by-market decisions, and nearly 675,000 UnitedHealthcare Medigap policyholders and 1.9 million UnitedHealthcare Medicare Advantage plan members will retain access to SilverSneakers in 2019.”I think it’s a smart move,” said Connie Holt, an independent broker with Goldsum Insurance Solutions of Pleasant Hill, Calif.But many of the company’s customers aren’t happy that SilverSneakers, which offers group classes tailored to seniors in addition to gym access at 15,000 sites, is disappearing. And confusion about alternatives is widespread.It’s one of the “top topics” that seniors have been raising over the past few months when they call Ohio’s Senior Health Insurance Information Program, said Chris Reeg, the OSHIIP program director.Michael Chanak Jr., 69, of Wadsworth, Ohio, had problems getting through to UnitedHealthcare’s customer relations department several times when he called with questions — a common complaint. “The way this is being implemented is a train wreck,” said Chanak, who has a UnitedHealthcare Medicare supplemental policy and spends an hour every day exercising at his gym.People are “extremely upset,” wrote Margaret Lee of Arroyo Grande, Calif., in an email. “That’s about the only topic of conversation at my water exercise class!”AARP has also become a target of anger because it endorses UnitedHealthcare’s Medigap and Medicare Advantage insurance policies — an arrangement that yields substantial royalties for the organization.In an email, Mark Bagley, a spokesman for the organization, said “[UnitedHealthcare], not AARP, operates these plans and determines the benefits.””I will be dropping my AARP membership when it is time to renew,” wrote Shelley Holbrook, 67, of Yorba Linda, Calif., a UnitedHealthcare Medigap policyholder, in an email exchange about the loss of SilverSneakers. “I am a Parkinson’s patient who has been prescribed this type of exercise program,” she explained. “This program is under the guidance of certified instructors that make sure the exercise routines are performed correctly. … An ordinary gym membership provides no instruction on how to use the equipment safely for seniors.””A health coach is not what I need,” Holbrook continued. “I have used the health coaches before, and have found them to be totally worthless.”For policyholders like Holbrook, the situation is complicated by another factor: Federal laws don’t ensure that seniors can switch Medicare supplemental insurance plans without undergoing new medical evaluations after an initial “guarantee issue” period. (This period occurs six months following a person’s enrollment in Medicare. Changes are allowed under a few specific circumstances and by laws in a few states.)If seniors can meet medical standards, they’ll find SilverSneakers available from other insurance operators. In 2019, Tivity Health is offering the program through more than 65 health plans covering more than 15 million older adults and introducing a new digital platform that emphasizes its social benefits: SilverSneakers Connect.”There are people we’ve learned who are alone but don’t want to go to the gym,” and the new platform can help them connect with each other as well as activities in their communities, said Donato Tramuto, Tivity Health’s CEO. Recent research suggests that SilverSneakers may help reduce isolation and loneliness in seniors who go to classes and form new relationships, he noted.Whether UnitedHealthcare’s health plans will be less appealing because of the shift away from SilverSneakers is yet to be determined. Several years ago, Humana, another giant insurer, also began reducing the number of plans that offered SilverSneakers, but it faced a backlash from members and sales representatives. “The membership perceives [SilverSneakers] as a valuable benefit despite the fact that not everyone uses it,” said George Renaudin, Humana’s senior vice president of Medicare.Humana subsequently reversed course and is now making SilverSneakers broadly available to about 3.5 million Medicare Advantage and Medigap policyholders.Ray Liss, who retired seven years ago, just changed over from UnitedHealthcare to a Humana Medicare supplemental policy with his wife. The loss of SilverSneakers precipitated the switch, which has an unexpected benefit: The couple will save almost $60 a month next year on their new policy.In an email, Liss, who declined to say where he lives, was philosophical about the value of exploring his options, writing, “I was pretty mad at the time, but it worked out for the best.”Kaiser Health News is a nonprofit news service covering health issues. It is an editorially independent program of the Kaiser Family Foundation that is not affiliated with Kaiser Permanente.KHN’s coverage related to aging and improving care of older adults is supported in part by The John A. Hartford Foundation. Copyright 2018 Kaiser Health News. To see more, visit Kaiser Health News.last_img read more

Tech Glitches Delivery Delays Apples Latest Product Rollout Has Been a Mess


first_img Geoff Weiss Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals September 12, 2014 Register Now » Next Article While consumer and media response to Apple’s forthcoming range of watches and smartphones has been decidedly mixed, one thing is fairly unanimous: the company’s rollout process seems to have been botched at every turn.Last night, when pre-order for the iPhone 6 and iPhone 6 Plus became available at 3 a.m. ET, online shoppers in the U.S. were vexed to arrive at a malfunctioning Apple store, which was down for a total of 2-1/2 hours.While some consumers were able to successfully order their phones via the Apple Store app for iOS, others tried their luck on carrier websites like AT&T and Verizon, reports CNET. Sprint and T-Mobile, meanwhile, were as glitchy as the Apple site itself.Related: Apple’s Big Announcements and What They Mean to You: The Weekly RoundupEven users who managed to place an order were met with unexpected delays: the iPhone 6 will deliver within seven to 10 business days, some shoppers reported, while the 6 Plus won’t arrive for another three to four weeks.Though the iPhone 5 also sold out upon its launch in 2012 at a record pace — causing Apple to prolong shipment times from one week to three — this reportedly marks the first time that Apple’s online store has completely crashed.Frustrated users took to Twitter to vent about the situation:Odd. If you hit refresh enough times when the Apple Store website is down you get this easter egg. pic.twitter.com/f9r5TggnoF— Jonathan Paull (@zamn) September 12, 2014Related: Leadership Lessons From Apple CEO Tim CookThe hilarious responses took a similar tone to the social avalanche on Tuesday when Apple’s livestream — during which the new products were to be officially unveiled — similarly crashed. As Apple doesn’t typically livestream its keynotes, those who tuned in were staggered to discover strange error screens, a Mandarin translation dubbed over the audio stream and a maddening string of stops and starts.Which all begs the question: could Apple have done better? While the onslaught of orders would seem to indicate that the company succeeded from a product perspective, the glitches may be a blight upon Angela Ahrendts, according to CNET — the former Burberry CEO who joined Apple in May to revamp its underperforming retail and online stores division.And as for the live stream failures?If you’re having a bad day, remember that there’s some guy that needs to tell Tim Cook that half the live stream had Chinese dubbing.— Josh Helfferich (@JoshHelfferich) September 9, 2014Related: The ‘i’ Goes Silent: Why Apple Didn’t Name Its Smartwatch ‘iWatch’ 3 min read Add to Queue Retail Center Former Staff Writer Tech Glitches, Delivery Delays: Apple’s Latest Product Rollout Has Been a Mess So Far Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. –shareslast_img read more

Progress Named a Leader in the New 2019 Gartner Magic Quadrant for


first_img Dmitri TcherevikGartnerMarketing Technology NewsNewsProgress Previous ArticleIntroducing Shutterstock Elements, Thousands of Cinema-Grade Video Effects for FilmmakersNext ArticleNot All Product Recommendations Are Created Equal Progress is one of 13 vendors evaluated for its completeness of vision and ability to executeProgress announced it has been recognized by Gartner as a Leader in the new 2019 Gartner Magic Quadrant for Multiexperience Development Platforms (MXDP).According to Gartner, “a multiexperience development platform (MXDP) offers professional and citizen developers a range of front-end development tools and back-end services that enable rapid, scalable development of seamless, targeted and ambient user experiences across devices and channels. The design-time and runtime tools and services are delivered via a unified development environment that has loosely coupled front- and back-end architectures.”2Progress was one of 13 vendors evaluated for inclusion within the Gartner Magic Quadrant for Multiexperience Development Platforms report. Gartner states in its research, “The MXDP market contains some of the largest enterprise software vendors that serve the needs of development teams. It also includes up-and-coming vendors that offer independent development platform options. All MXDPs support the need of professional developers to use high-control development tools (in order words, code-centric tools), and most also support development using low-code approaches for higher developer productivity. However, the primary purpose of these platforms is not to support low-code development, but rather the creation of multiple types of app in support of the digital user experience across devices and interaction modalities.”Marketing Technology News: M-Commerce Not Living up to Consumer Expectations, New Research FindsWith a focus on the professional developer, the Progress Kinvey platform brings together the best of the Progress portfolio by providing the most modern high productivity platform for building and deploying consumer-grade enterprise apps. It comes equipped with:A cloud-native serverless backendLow-code development capabilities in Kinvey StudioAI-driven Kinvey ChatThe open source development framework for native mobile app development, NativeScriptThe most complete UI development toolkit for JavaScript from Kendo UICognitive capabilities in Kinvey AI/ML, for building and deploying analytical modelsThe largest set of integrations on the market with Kinvey Data Pipeline, powered by DataDirectMarketing Technology News: Zeta Global and PlaceIQ Announce Strategic Partnership to Enhance the Zeta Data CloudIn addition, Progress Kinvey increases productivity by uniquely providing DevOps and enterprise security with a fully managed service and a microservices framework for enterprise data integration. These capabilities ensure that the most modern apps can scale when connected to backend enterprise systems, seamlessly. The entire platform is non-proprietary and compatible with a standard JavaScript development toolkit, ensuring developers have the freedom to work how they want with the tools they prefer.“We give our customers multiexperience capabilities within a single platform for developing and deploying apps across any channel. When coupled with our ability to support digital experiences across any touchpoint – mobile, web, PWAs, wearables and more, organizations are able to create truly transformative and personalized digital experiences,” said Dmitri Tcherevik, CTO, Progress. “In our opinion, Gartner’s acknowledgement of us as a Leader in the MXDP Magic Quadrant is a testament to our ability to deliver and we’re truly humbled by the recognition.”Marketing Technology News: Beanstalk Digital Launches Beanstalk Predictive to Provide Robust Data Analytics Through AI-Driven Insights Progress Named a Leader in the New 2019 Gartner Magic Quadrant for Multiexperience Development Platforms PRNewswireJuly 16, 2019, 10:45 pmJuly 16, 2019 last_img read more

For California attorney general Xavier Becerra resistance is personal


first_imgReviewed by Kate Anderton, B.Sc. (Editor)Feb 4 2019When President Donald Trump demands a border wall or threatens to deport young unauthorized immigrants, one of the loudest opposition voices comes from the son of Mexican immigrants — who also happens to be California’s top lawyer.Democrat Xavier Becerra, the state’s first Latino attorney general, is not only one of Trump’s biggest critics, he is an unrelenting adversary in court, striking at Republican efforts to overturn federal rules not just on immigration, but on health care, birth control, climate change and more.On Tuesday, Becerra, 61, will take the national stage when he gives the Spanish-language rebuttal to the president’s State of the Union address. He has challenged the Trump agenda before.Becerra has taken the Trump administration to court 45 times since former Gov. Jerry Brown appointed him to the job in 2017. In November, voters overwhelmingly gave him a four-year term, validating his decision to leave Congress after 24 years.Becerra, whose wife is a doctor, is leading a coalition of 20 states and the District of Columbia in defending the Affordable Care Act against a Texas lawsuit that could determine the fate of the law — and with it, health coverage for millions of Americans. And he won a nationwide court injunction last year that blocked the Trump administration’s decision to end the Deferred Action for Childhood Arrivals (DACA) program, which allows qualified young people who were brought into the U.S. illegally as children to obtain temporary work permits.When news reports last month revealed that Trump was considering diverting emergency disaster relief funds from California, Florida and Texas during the partial federal government shutdown, Becerra condemned the president on Twitter for poaching funds for a “reckless & lawless” border wall.The fights are ones that Becerra describes as personal. He talked to California Healthline’s Samantha Young about his role — and how his upbringing influences his legal decisions.The following interview has been edited for length and clarity.Q: You were a veteran member of Congress in a leadership role. Why did you take this job? November 2016 hits. We have the election. All the things that I cared about were going to be placed in jeopardy by this new president.I found myself thinking I probably could make a bigger difference as the attorney general for the entire state of California, defending everything I fought to erect, than as a minority member in the House of Representatives trying to make my point, but always losing.I made a calculation. I think I made the right choice.Q: You have sued the Trump administration 45 times on education, immigration, health care, birth control access, climate change and more. What’s the one case you really wanted to win?I’ll give you two.First, the Affordable Care Act, knowing how much it has been a game changer for families. I would never have believed that I’d be leading the effort to protect the entire Affordable Care Act as an attorney general for one of 50 states. But here I am.The second one is the DACA litigation, because as the son of immigrants, I watched my parents struggle and saw the things they had to live through. I believe these DACA recipients are going to be some of the greatest leaders America has and it’s because they had to go through so much like my parents did. So, it’s very personal.Q: Do you remember your parents’ economic struggles as a child?I thought I was middle class growing up as a kid. It really wasn’t until I was driving with my mom to start my first day at Stanford University, driving through Palo Alto, that I realized I’m not middle class.We always had decent food to eat. I never got a pair of Converse. I never had a pair of Levi’s jeans. Never had that kind of stuff, but I always had clothes. It didn’t dawn on me that we were much different than other folks.Related StoriesAn active brain and body associated with reduced risk of dementiaResearchers identify gene mutations linked to leukemia in children with Down’s syndromeResearch reveals genetic cause of deadly digestive disease in childrenQ: How does your upbringing influence your decisions as attorney general?Everything I do is informed by what I grew up with. I defend immigrants with a passion because I saw immigrants every day of my life. And I know how hard they work. I never saw a day where my dad didn’t work.My mom came here when she was 18 from Guadalajara, when she married my dad. Didn’t know English. Learned it. She could always find a job, and when she learned English it became easier. But she could never go very high because she never went to college.So, when someone wants to knock an immigrant, you’re knocking my dad and my mom.Q: You believe everyone should have access to health care. Was there ever a period in your life when you didn’t have health insurance?I don’t ever recall a time when I didn’t. That’s why I’m such a big defender of unions. My dad was a construction worker. My dad got to the sixth grade. As difficult as it is for someone with a sixth-grade education to get a decent job, and while being a manual laborer and working construction doesn’t make you a millionaire, if you work for a union it gets you basic benefits.I knew what it meant to have health insurance, especially on the day my mom ended up having a miscarriage. She was hemorrhaging at home and she had to be rushed to the hospital. There was no hesitation.We knew we could go to the doctor — and everybody should know that. For me, health care is a right. I’ve been a single-payer advocate all my life.Q: Why do you think it’s important to build coalitions with other states when challenging the Trump administration?Lifting something by yourself is very difficult. When you get a team to do it, it just clicks so much easier. Maybe it’s because I went through Congress more years in the minority than the majority, where you realize what it takes to actually cobble together a coalition to get something done. Or, maybe it’s just that when you’ve been in a minority all your life, the son of immigrants with very little, you know it takes a team effort.I got through Stanford knowing my family didn’t have a lot of money, so I had to work, take out student loans and receive help from the government. It was a combination of a lot of things.Q: What’s your response to critics who say state attorneys general are “militarizing” their office to overturn policies your party can’t block in Congress?Which of the cases should we not have filed? The one to defend the Affordable Care Act, or the one to prevent women from losing access to birth control, or is it the one to allow DACA Dreamers to be deported, or is it the one to make sure that we are defending against a crazy border wall, or is it the one that should allow predatory for-profit colleges to continue to avoid having to provide relief to students who were defrauded?We’re not doing this because we’re trying to attack the federal government or because we’ve got it out for this particular president. How would we explain to the people who would have been unprotected why we just watched, why we just spectated?This KHN story first published on California Healthline, a service of the California Health Care Foundation. This article was reprinted from khn.org with permission from the Henry J. Kaiser Family Foundation. Kaiser Health News, an editorially independent news service, is a program of the Kaiser Family Foundation, a nonpartisan health care policy research organization unaffiliated with Kaiser Permanente.last_img read more

Researchers create online tool to determine genetic diversity and ancestry of cell


first_imgReviewed by Kate Anderton, B.Sc. (Editor)Apr 5 2019Cancer is a highly varied disease, with genetic differences among different tumor types, individuals and ancestral populations. These genetic differences can impact disease aggressiveness, the type of disease, and the response to therapy. It is important that scientists have proper tools and model systems to study how these variations affect cancer development and devise effective therapies for patients of all genetic backgrounds. In a new paper published in Cancer Research, Moffitt Cancer Center researchers, in collaboration with scientists at Ponce Health Sciences University in Puerto Rico, investigated this issue by creating an online tool that can be used by scientists to determine the genetic ancestral origin of more than 1300 different cell lines.In cancer research, cell lines established from patient tumors are used in laboratory experiments as model systems to understand the molecular and cellular basis of cancer, identify therapeutic targets and develop novel treatments. However, the genetic ancestry of these cell lines is often unknown or incomplete. As a result, scientific data may not accurately reflect the diverse populations that exist throughout the world, resulting in less effective patient management and treatments for different populations.The research team performed an extensive set of analyses to improve on this knowledge gap by examining the genetic ancestry of 1,393 cancer cell lines based on known populations. They found that these commonly used cell lines do not represent the diverse ancestry of the human population. The majority, 62.46 percent, of the cell lines were determined to be from European origin, while 29.18 percent were from East Asian origin. All other populations were represented by less than 10 percent of the analyzed cell lines, including 5.26 percent of African origin, 0.86 percent of African American origin and 1.95 percent of Hispanic/Latino origin. Additionally, many ancestral populations were largely absent or underrepresented in cell lines for specific cancer types. For example, African American men are known to be diagnosed with prostate cancer at a younger age and have a higher risk of dying from the disease than other populations. However, only 1 out of 10 prostate cancer cell lines was found to represent African ancestral genetic factors.Related StoriesStudy: Causes of anorexia are likely metabolic and psychologicalSlug serves as ‘command central’ for determining breast stem cell healthHealthy lifestyle lowers dementia risk despite genetic predispositionWith the information they obtained, the team created an online, interactive web-based tool that allows researchers to determine the genetic ancestry of cell lines. “This information can be used by scientists as a data and visualization tool to show the genetic ancestry of the cell lines they are using for experiments,” said Steven Eschrich, PhD, lead author of the article and senior member of the Biostatistics and Bioinformatics Department at Moffitt. “We believe that this new tool, representing diverse ancestries, will be an important resource to reduce the knowledge gaps that exist about disease prevention and treatment among diverse ancestral populations.””We expect this resource to allow researchers access to ancestry in cell line models and to contribute to efforts to address the underrepresentation in cancer types with clear disparities. Incorporating estimated genetic ancestry within cell line molecular biology and drug discovery studies can significantly improve the rigor, reproducibility and relevance of cancer research activities, not just those explicitly examining the role of genetic ancestry in cancer biology,” said Julie Dutil, Ph.D., professor at Ponce Health Sciences University. Source:https://moffitt.org/newsroom/press-release-archive/2019/moffitt-cancer-center-researchers-develop-interactive-tool-to-estimate-genetic-diversity-and-ancestry-of-cancer-cell-lines/last_img read more

Study examines potential advantages and disadvantages of blister packaging for nursing homes


first_imgProcess of report productionIn June 2018, the German Ministry of Health commissioned IQWiG to prepare the report as a rapid report in an accelerated procedure. Interim products were thus not published and did not undergo a hearing. The present rapid report was sent to the Ministry on 29 March 2019.Source:Institute for Quality and Efficiency in Health Care The discrepancy between the broad and sometimes vehement debate about blister packaging on the one hand and the lack of evidence on the other surprised us. Individual stakeholders and interest groups passionately argue for or against blister packaging, without being able to scientifically support their pros or cons. It is good that the commission from the Ministry of Health has now disclosed this.” Against this background, IQWiG developed the design for a future study and integrated it into the report. Thomas Kaiser affirms: “Our research has shown that high-quality studies are indeed available on other research questions in residential long-term care and that such studies are evidently feasible.”Thomas Kaiser, Head of the Drug Assessment Department, IQWiG Reviewed by James Ives, M.Psych. (Editor)May 20 2019In blister packaging, a pharmacy (or a service provider commissioned by it) portions and packs the prescribed drugs of a patient according to weekdays and times of day, sorted into individual transparent packages (blisters). In this way, one can see at a glance when tablets should be taken and whether all tablets have been taken as planned.For some years now, there has been a broad and controversial debate in Germany as to whether increased blister packaging for nursing home residents is suitable for relieving the burden on the long-term care system and sustainably improving the care of nursing home residents. The German Federal Ministry of Health therefore commissioned the Institute for Quality and Efficiency in Health Care (IQWiG) to examine, among other things, findings from studies. The report is now available.According to IQWiG’s search for evidence, studies on patient-specific blister packaging have so far been predominantly conducted for the outpatient sector, also internationally. However, as far as blister packaging for nursing homes is concerned, hardly any robust data from studies are available. Even the common arguments put forward by various stakeholders and interest groups for or against more blister packaging in nursing homes are not scientifically proven. This also applies to the aspect of cost-effectiveness.Possible advantages and disadvantagesIn the opinion of its advocates, the fact that medication errors will occur less frequently with blister packaging supports the introduction of this method. Because the more illnesses a resident suffers from, the more complex drug therapy becomes. In addition, if nursing staff were relieved of the burden of organizing the administration of drugs, they would have more time to care for the individual patient. And this in turn could increase job satisfaction in nursing and make the profession more attractive for young people.Critics, however, fear a loss of competence if tasks are increasingly shifted from nurses to other professional groups. Moreover, patients might also lose some of their autonomy because they would be even less able to recognize and decide which drugs to take and which not. Critics also point out that not all drugs are “blisterable”. This could even complicate the administration of drugs for nursing staff in nursing homes, as they would have to remember a second distribution of drugs in addition to the tablets in the blisters.Initially, blister packaging causes additional costs. However, these should at least in part be compensated if wastage is reduced. The fact that not every patient receives a full package, but only individual tablets in the blister, means that overall, fewer tablets are thrown away.Studies examine blister packaging in the outpatient sectorThe IQWiG researchers found a number of studies that investigated aspects of the benefit of blister packaging, but they all referred to an outpatient setting; however, such studies can hardly be transferred to residential settings. This holds especially because people who live at home should still be able to handle their medication themselves. No study investigated residential geriatric long-term care.Related StoriesSecurity cameras installed in nursing homes may do more harm than goodNew computational framework reveals impact of arthritis drugs on gene expressionStudy: Stress experienced by premature infants can carry on throughout their adult lifeThe studies originating from Germany are mainly before-and-after comparisons without a control group, which were evaluated in model projects by health insurance funds. However, the results of such studies are not very meaningful from a scientific point of view – both with regard to the benefit for nursing home residents (symptoms, state of health, side effects of medication, etc.) and for the nursing staff (professional competence, work-related quality of life, etc.). IQWiG concludes that the benefit and harm of blister packaging in nursing homes therefore remain unclear.Statements on cost-effectiveness can only be made by means of estimationThe evidence on the cost-effectiveness of blister packaging for nursing homes is also insufficient, but the Institute was able to estimate possible effects based on various sources. IQWiG assumed that a weekly blister costs about €3 and that drug expenditure will decrease by 4.1% due to less waste. If at least €73.17 of costs for blistered drugs are incurred per week and resident, blister packaging would be cost-neutral. This, however, refers only to drug costs. Due to a lack of data, it is not possible to consider other monetary effects (e.g. due to fewer hospital referrals).Statements on non-monetary effects are also uncertain: Assuming that about half to two thirds of the approximately 818,000 people needing full residential nursing care in Germany receive blister-packed drugs, the time savings for nursing staff would amount to about 22 to 51 minutes per month and resident.Great need for research: IQWiG proposes a design for a new studyThe Institute has identified a great need for research on blister packaging in nursing homes.last_img read more

Research shows beachgoers negatively impacted by offshore oil platforms


first_img Provided by University of Delaware More information: Jacob R. Fooks et al. Continuous attribute values in a simulation environment: Offshore energy production and Mid-Atlantic beach visitation, Energy Policy (2017). DOI: 10.1016/j.enpol.2017.08.005 In some areas, California beach fans must live with offshore oil platforms. UD research indicates 16 percent of Delaware beachgoers would not go to a beach with oil platforms looming offshore. Credit: University of Delaware Citation: Research shows beachgoers negatively impacted by offshore oil platforms (2018, June 21) retrieved 18 July 2019 from https://phys.org/news/2018-06-beachgoers-negatively-impacted-offshore-oil.html But if offshore energy platforms—especially oil rigs—were installed off the Delaware coastline, many of those visitors would move their beach blankets elsewhere, according to University of Delaware research.Forty percent of beachgoers responding to a UD survey that was administered in 2012 said their vacation experience would be negatively impacted, and 16 percent indicated they simply would not visit the beach with oil platforms looming offshore.The research was led by Jacob Fooks, who was a doctoral student in economics at UD when the research was conducted, and Kent Messer, the Unidel Howard Cosgrove Chair for the Environment in UD’s College of Agriculture and Natural Resources (CANR).Josh Duke, professor in the Department of Applied Economics and Statistics, and George Parsons, professor in the College of Earth, Ocean, and Environment, are also authors on the paper which was published recently in the journal Energy Policy.Messer said the results from the study should worry the leaders of beach communities who may be considering these offshore energy sources because they could experience a drop off of 10 to 15 percent of their visitors.”Can the beach communities lose 15 percent of their tourists?,” Messer said. “These people will go elsewhere and another 25 percent of the group is going to come and not really enjoy their visit as much. That’s a big impact.”The research was conducted at Rehoboth Beach and Cape Henlopen from July 12–15 and July 29–August 1 in 2012.A total of 525 people participated in the research by completing either a short survey about their opinions regarding a series of images of oil platforms and wind turbines offshore at various distances or by taking a more in-depth, longer survey using computer simulations that presented images of oil platforms or wind turbines on the horizon at varying distances.In both surveys, participants were shown oil platforms and wind turbines at different distances and asked if those structures would have enhanced, detracted or made no difference to their beach experiences.Around 60 percent of those who took the short survey indicated that oil platforms would detract from their beach experience, compared with 25 percent for the wind turbines.Those who took the longer survey were able to select a starting location for the energy platforms.”Even at ten miles out, which was the farthest the participants could place the oil platforms, many of the respondents would not visit the Delaware beaches at this distance—even though they wouldn’t be able to see the platforms,” Messer said. “Participants were clearly concerned about the oil spills that could affect the beaches. In contrast, people were more comfortable with having wind turbines closer to the shore.” In January 2018, the Trump Administration announced a new five-year drilling plan that could open new areas along both U.S. coasts. Messer said that it is important for coastal communities to realize the negative view many of their visitors have for offshore oil drilling structures.”Our research shows that beach visitors do not like these oil platforms and believe they would detract from their experience,” Messer said. “A bunch of people said they wouldn’t come to the Delaware beaches because of the presence of offshore oil platforms and a bunch of people indicated a negative sentiment, basically saying, ‘I will still come to the beach but you’ve taken a bunch of the fun out of it.’ This negative sentiment is important from a consumer welfare perspective. If you go somewhere and you don’t like it, that’s a real loss to society.” Every year, visitors flock to Delaware’s beaches for an opportunity to relax, soak up the sun and take a dip in the ocean.center_img Journal information: Energy Policy Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Near-shore wind farms would have big impact on coastal tourismlast_img read more

General Motors to invest 22M more in Tennessee facility


first_img The automotive manufacturer made the announcement Thursday about the growth at the Spring Hill facility.The company says the investment will let the plant build 6.2-liter V8 engines with GM’s dynamic fuel management technology, which uses 17 cylinder patterns to optimize performance.GM is also finishing a $300 million investment at Spring Hill that will bring more than 200 new jobs to produce the new Cadillac XT6.The facility opened in 1990 and employs about 3,800 people. GM says it has invested more than $2 billion at the complex since 2010. © 2019 The Associated Press. All rights reserved. Citation: General Motors to invest $22M more in Tennessee facility (2019, January 24) retrieved 17 July 2019 from https://phys.org/news/2019-01-motors-invest-22m-tennessee-facility.html Auto supplier Denso: $1B investment in Tennessee plant This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further General Motors says it plans to invest another $22 million in its Tennessee manufacturing facility to build more engines.last_img read more

Domestic operations at Terminal 1 to be inaugurated on Dec 12


first_imgThe international terminal, constructed at a cost of Rs 1,100 crore, was opened to international passengers last year. December 05, 2018 COMMENTS At present, the total capacity of the solar plants at CIAL is 30 MW   –  File photo SHARE Published oncenter_img SHARE SHARE EMAIL COMMENT airlines and aviation Cochin International Airport Ltd (CIAL) said that domestic operations at the renovated Terminal-1 and the enhancement of the solar power production capacity to 40 MWp would be inaugurated on December 12.Kerala’s Chief Minister Pinarayi Vijayan will inaugurate the two mega projects of the CIAL, which had handled one crore passengers in the fiscal year 2017-18.The international terminal, constructed at a cost of Rs 1100 crore, was opened to international passengers last year.As there has been a steady growth in the domestic passengers, the renovation work of Terminal-1, which earlier handled international operations, with most modern facilities, was started one and a half years ago.V J Kurian, CIAL Managing Director said that the domestic aviation market has been witnessing stupendous growth.“The national Year-On-Year growth in this sector is 18 per cent, whereas CIAL has been experiencing 24 per cent,” he said.As the first fully solar operated airport in the world, CIAL has been internationally acclaimed with various honours, including the ‘Champions of the Earth’ award constituted by the United Nations.At present, the total capacity of the solar plants at CIAL is 30 MW.As Terminal-1 is ready for operation, the production capacity has to be increased to meet the complete power needs of the airport.“The project to install solar panels on the roof of the car park at Terminal-1 was part of this.As the airport receives the power from these panels, the total solar power capacity will be raised to 40 MWp. This project is also being commissioned on 12 December”, CIAL said.With the commissioning of the new solar carport for Terminal-1, the total installed capacity of the carports will be 5.1 MWp and it would be able to house 2600 cars, it said.“Here also, CIAL sets another record as an airport having the largest solar carport in the world, surpassing the Wieze International Airport, Germany, the present record holder, with an installation capacity 4 MWp.CIALs 5.1 MWp solar carport is the largest solar carport in India, it said.last_img read more

Thankful to BJPRSS for opportunities to take ideological battle to people says


first_imgThankful to BJP-RSS for opportunities to take ideological battle to people, says Rahul GandhiRahul Gandhi is in Ahmedabad to appear before a metropolitan court in a defamation suit filed against him by the Ahmedabad District Cooperative Bank and its chairman.advertisement Next Press Trust of India AhmedabadJuly 12, 2019UPDATED: July 12, 2019 15:26 IST Congress leader Rahul Gandhi arrived in Ahmedabad on Friday to appear before a court in a defamation suit filed against him. (File Photo)Congress leader Rahul Gandhi on Friday said he was thankful to his opponents in the RSS and the BJP for providing him with opportunities to take his ideological battle against them to the public.Rahul Gandhi arrived in Ahmedabad to appear before a metropolitan court in a defamation suit filed against him by the Ahmedabad District Cooperative Bank and its chairman Ajay Patel.”I’m in Ahmedabad today, to appear in another case filed against me by my political opponents in the RSS/BJP. I thank them for providing me these platforms & opportunities to take my ideological battle against them to the public. Satyameva Jayate,” he said in a tweet after reaching Ahmedabad.The defamation suit alleges that Congress leaders, including Gandhi, had falsely claimed that the bank was involved in a “scam” to swap Rs 750 crore in scrapped notes with valid currency within five days of demonetisation in 2016.The defamation suit was filed last year after Gandhi and Surjewala claimed that the Ahmedabad District Cooperative Bank was involved in a “scam” to swap Rs 745.59 crore in swapped notes with valid currency within five days of demonetisation announcement on November 8, 2016.Union home minister Amit Shah is one of the directors of the ADC Bank.The court issued summonses to the two leaders on April 9 after finding prima facie evidence against them.The complainants said that the Congress leaders leveled “false and defamatory allegations” against the bank.The court had conducted an inquiry under section 202 of the Code of Criminal Procedure before summoning Gandhi and Surjewala.The section deals with inquiry to decide whether there is sufficient ground for proceeding against a person.Gandhi and Surjewala’s allegations were based on the reply given by the National Bank for Agriculture and Rural Development to an RTI query of a Mumbai-based activist.ADCB and Patel have denied that the bank exchanged such a huge amount of swapped currency as alleged.READ | Rahul Gandhi issued summonses by two Gujarat courts in defamation casesWATCH | In Depth: The big Congress churnFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySumeda Tags :Follow Rahul Gandhilast_img read more

Punjab CMs wife Preneet Kaur faints at cleanup drive


first_img Next Indo-Asian News Service ChandigarhJuly 13, 2019UPDATED: July 13, 2019 14:04 IST Punjab CM Amarinder SinghPatiala MP and Punjab Chief Minister Amarinder Singh’s wife, Preneet Kaur, fainted at a plastic cleanup campaign in her constituency on Saturday, officials said.Kaur, 75, collapsed as she arrived at the event to flag off the Swachhta Shramdan drive to clean up plastic.She got her blood pressure checked and that was fine, a doctor told IANS.She later tweeted by saying that she successfully launched the Swachhta Shramdan drive under the Punjab Pollution Control Board.”Under this initiative, we are making Patiala polythene-free. I urge all of you to join this movement and help us make our surroundings cleaner,” she said.Also read: How Amarinder Singh held his fort against Modi waveALSO WATCH| Watch: PM Modi’s full speech at NDA’s Parliamentary board meetFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byIram Ara Ibrahim Punjab CM’s wife Preneet Kaur faints at cleanup driveShe collapsed as she arrived at the event to flag off the Swachhta Shramdan drive to clean up plastic.advertisementlast_img read more

Corona beer brewer


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"I am happy to see India’s rise in the last two years." he said. While Trump was responding to what many took as another attack on a woman, I lacked the basic foundation or springboard with which I would have launched myself into the career. are seen in this Bush family photo taken in Kennebunkport, however, which was thrown into turmoil after long-time leader Muammar Gaddafi was toppled in a NATO-backed uprising in 2011. Updated Date: Apr 09, As this Firstpost? it is.

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Attahiru said.The 112 rooms and villas were designed by British architect Norman Foster. I want that big bum as soon as I can get him. Frazier landed one more roundhouse left,com. endorses the research. But in the last few years I have learned a great deal more about taking care of things. to be good to other people and to know that you are a part of their smile! When U. read more