LG G6 Plus Specs VS original Whats changed

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first_imgStory TimelineYou can also make a transparent LG G6 if you’re brave enoughLG G6 mini might be coming soonNetflix for Android gets HDR support (but only for the LG G6)LG G6 Unlocked version release date today for most carriersLG G6 Pro, G6 Plus to herald new “premium derivative” lineHere’s how to avail of the LG G6’s Second Year PromiseLG G6+ and G6 32 GB models are finally official The LG G6 is being released soon with a newly boosted 32GB of internal storage. With a Hi-Fi Audio Recorder and the same display, processor, and RAM as before, the LG G6 is still a high-end contender for best smartphone on the block. This new 32GB internal storage size version will cost users around $700 USD.SEE TOO: Our full LG G6 ReviewThe internal storage size of the device called LG G6+ (or Plus) is 128GB. This will come in handy when the user starts to utilize their 32-bit Hi-Fi Quad DAC for audio. The highest quality sound files will be needed to take full advantage – and they aren’t tiny. The LG G6 Plus will also ship with a pair of earphones from B&O Play. This makes the higher-quality audio feel a bit more solid as it blasts one’s eardrums with great finesse. Wouldn’t want to be blasting eardrums with low-end buds, would we?The LG G6 and LG G6 Plus will be coming in a series of colors both classic and new – new as in not available for all models before. This includes Black and Platinum, which were out before, as well as Optical Marine Blue and Terra Gold.The LG G6 that’s already out on the market will get a software update this summer that adds a set of new feature abilities. These same abilities will be available on the LG G6 with 32GB internal storage and the LG G6 Plus. These features include a new Face Print screen unlock using the device’s front-facing camera, a Low Power Consumption mode, and a Covered Lens warning for the camera. This week the folks at LG have introduced a new set of features for the LG G6 as well as a new phone: the LG G6 Plus. The difference is in the device’s ability to carry massive amounts of media as well as the device’s newly boosted sound quality. This is the first time LG has released a device in this manner – generally they tend to release smartphones partway through the year with completely different names rather than crowning one that they released earlier.last_img read more

Galaxy Note 8 release date price and specs leaked

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first_imgFor the Samsung Galaxy Note 8 this morning several key details were leaked surrounding the release and pricing of the handset. Previous leaks suggested sizing and contents of the smartphone, closely resembling those of the Samsung Galaxy S8 Plus. This device’s specifications are only slightly different from those of the previously released handset, with a few key details in place to make this the most powerful Samsung smartphone released in history. The Samsung Galaxy S8 Plus featured a Qualcomm Snapdragon 835 processor – the same goes for the Galaxy S8 non-Plus, in standard size. The difference with the Galaxy Note 8, which also sports the same Snapdragon, is that there’s a bit more RAM to roll with. Instead of working with 4GB of RAM, this device has 6GB. This device has a 3,300mAh battery according to the most recent set of leaks. That’s a bit different from the Samsung Galaxy Note 7, which originally came with a 3,500mAh battery. Moving away from that capacity might make sense in the public eye due to the inconvenient heat-related nature of the Galaxy Note 7 – but it’s also odd. It’s odd that the Note 8 would have a 3,300 battery since the Galaxy S8 Plus has a battery with 3,500mAh capacity. After all, it’s not the capacity that caused the fires, it was the construction of the batteries and connectors and etcetera.The backside of this device will have a set of lenses, making it one of the few smartphones in the world to have a dual-camera setup. This setup is becoming more and more popular with the rise of Sony’s dual-camera image processing finesse, coming to brands like Apple, Huawei, and Xiaomi – amongst others. The Galaxy Note 8 is said in Venture Beat to have a set of 2x 12-megapixel cameras with optical image stabilization, the both of them. The camera array will appear near the fingerprint sensor, which will appear in a bundle with the LED flash and the device’s heart rate sensor. Samsung Galaxy Note 8 Specifications (Unofficial)• Display: 6.3-inch Super AMOLED Quad HD+ display – Infinity Display style – spilling over the edges• Processor: Qualcomm Snapdragon 835 processor — Octa core (2.3GHz Quad + 1.7GHz Quad), 64 bit, 10 nm process / for Global versions: Samsung Exynos 8895 processor — Octa core (2.35GHz Quad + 1.9GHz Quad), 64 bit, 10 nm process• RAM: 6GB• Internal Storage: 64GB USA / 64/128GB China• Camera: 2x back-facing 12 MP, f/1.7, 26mm, phase detection autofocus, OIS, LED flash• Front-Camera: 8 MP, f/1.7, autofocus, 1440p@30fps, dual video call, Auto HDR• Battery: 3300mAh• Connectivity: USB-C, Bluetooth 5, Wi-Fi, 4G LTE, 3G, nanoSIM, NFC• Additional: DeX computing technology, Fingerprint Scanner, IP68 water/dust resistance, Wireless ChargingSEE: How Galaxy Note 8 may be flawedThe above specifications are based on the past several weeks of leaks and insider tips from anonymous sources. Until Samsung releases the full set of specs themselves, there is no guarantee what the Galaxy Note 8 will contain. Today’s leaks tweaked what’s found above – and the same source as the cameras bit suggest the release date and pricing.The release isn’t tacked down to a single date yet, apparently, but should appear in stores in late September, 2017. This release will almost certainly be similar to past releases on major carriers in the United States, with several colors not unlike those released in the past. Pricing is tipped at around 999 Euro. That would be $925 or so if previous pricing setups remain true, or $1120 if directly converted from Euro to USD. Story TimelineGalaxy Note 8 may debut Qualcomm’s new flagship chipGalaxy Note 8 announcement rush could cost Samsung againGalaxy Note 8 benchmark confirms fears of no Android OGalaxy Note 8 skips onscreen fingerprint sensor due to this flawGalaxy Note 8’s US unveiling date might not be that soon after allSamsung execs can’t stop whispering Galaxy Note 8 secretslast_img read more

Razer Phone camera promised to improve with software updates

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first_imgAs we still don’t have much data to work on, it’s is rather too early to say where in the spectrum the Razer Phone’s camera lies. It has dual 12 megapixel sensors on its back, one with an f/1.7 wide-angle lens and another with an f/2.6 2x telephoto lens. Tan assures, naturally, that the hardware is already superb. All it needs is a few software finishing touches.In the coming weeks, the camera software will see some improvement on the performance side, with emphasis on shutter speed and low light output. This follows an update already rolled out last week which focused on stability and accuracy.Perhaps more interesting is what Razer has planned for the coming months, not weeks. That includes an “instazoom” features that will make the camera instantly, and jarringly, jump to the telephoto lens and 4x slow motion recording. Features that won’t be coming until an Oreo update in the first quarter next year include portrait mode and 60 fps video. Tan shared some sample photos, one of which does seem to have that much sought-after bokeh effect. There seems to be a trend among smaller smartphone makers these days. Launch a phone with a decent, or in Essential’s case, bad, camera experience and just promise improvements to come via software updates in the near or distant future. That was basically what happened to the Essential PH-1, which launched to a rather rocky start, and is now being applied to the Razer Phone as well. Razer CEO Min-Liang Tan took to Facebook to outline what lies ahead for the camera of a smartphone that is mostly geared towards gaming and entertainment consumption rather than creation. The Razer Phone brands itself as the gamer’s phone, with features like 120 Hz refresh rate and dual front-blasting Dolby Atmos speakers. And while the specs look great on paper as well as for the price, Razer will need to do more than bank on its name and tech to really sell the Razer Phone.SOURCE: Min-Liang Tanlast_img read more

Motorola One Power photo shows the Android One iPhone X

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first_imgThis “hands-on” photo, courtesy of 91mobiles, shows what is without question not the iPhone X. Aside from the obvious Motorola boot screen, there is also a good deal of chin at the bottom, one thing that no iPhone X “inspired” phone has been able to accomplish yet. Yes, there is a notch, but what sensors will live in that notch hasn’t yet been revealed.The site has no image of the back of the device but does state that there’s a vertical dual camera there. Whether it’s in the center or the corner of the phone, like the iPhone X, it doesn’t say, though the previous leak isn’t that encouraging. The iconic Motorola “batwing” logo sits right in the middle, which will supposedly also house the fingerprint sensor.It’s not yet certain whether the Motorola One Power will be a one-off thing or is the first of a new line of Motorola One phones. If it is the latter, it could mean that Motorola aims to create a niche market of Android One phones. Hopefully not all of them will look like the iPhone X, front and back. It seems that Lenovo and Motorola have a bittersweet present for its fans. On the one hand, it has yet another Android One phone to follow in the Moto X4’s footsteps. On the other hand, they will have to live with being taunted for using an iPhone X knockoff. Such is the reality that face interested owners of what is being called the Motorola One Power, which is being confirmed by a new leaked photo showing the device in all its glory. AdChoices广告last_img read more

Nissan ProPILOT Assist debuts on 2018 Nissan Rogue

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first_imgNissan has announced that its ProPILOT Assist technology will land on the 2018 Rogue SUV. This new feature is able to reduce driver workload during stop and go traffic by controlling acceleration, braking, and steering during single lane driving. Nissan says that ProPILOT Assist is the foundation for autonomous vehicles of the future. Drivers can use ProPILOT Assist to maintain lane control, navigate stop and go traffic and maintain vehicle speed and a set distance from the vehicle in front. Nissan will offer ProPILOT Assist as an option on the 2018 Rogue SL as part of the Platinum Package. The expected starting price of the Platinum Package Rogue is under $35,000 and it will hit lots later this month.The next Nissan vehicle to get ProPILOT Assist will be the Nissan Leaf in January of 2018. Nissan will roll the feature out to more models available in the US, Europe, Japan, and China with ten models to be launched by 2020 with the ProPILOT Assist.The 2018 Rogue will come in S, SV, and SL trims. Other than the ProPILOT Assist available, the Rogue line also has EZ Flex Seating System and a Divide-N-Hide Cargo System. Rogue models for 2018 get standard NissanConnect with Apple CarPlay and Android Auto on all trim levels.For 2018 the Rogue Midnight Edition package is being revised, but it’s not clear what those revisions are. Nissan has plans for the future of ProPILOT Assist and within two years the feature will be able to assist with steering, braking, and acceleration during multi-lane driving. Within four years there will be assisted steering, braking, and acceleration in city driving.last_img read more

Oculus Quest and Rift S released How to choose

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first_imgResolution has also taken a bump up with this release, with Oculus boasting a 42% increase in the Rift S over its predecessor. Total resolution clocks in at 2560 x 1440, which works out to 1280 x 1440 per eye. It sounds like a solid VR headset, but if you don’t like the idea of being tethered to a PC, the Rift S might not be best option. Today is a pretty big day for the folks at Oculus, as the company is launching two new virtual reality headsets. Coming out of the gate today are the Oculus Rift S and Quest, and though the goal of each headset may be bringing VR to the masses, they both do it in very different ways. The headset you go for ultimately depends on what kind of set up you’re looking to have. Story TimelineOculus Quest detailed: Freedom between Go and RiftOculus Quest nabs Beat Saber as a launch titleOculus Quest and Rift S release date and order info: Starting now This is where the Oculus Quest comes in. The Quest is riding a lot of excitement and hype as it enters release because it promises wire-free virtual reality that’s a fair bit more powerful than what we’re used to. Tracking is done through sensors on the headset and in the Touch controllers, and the headset itself is outfitted with a Snapdragon 835 chipset and a 72Hz OLED display with a total resolution of 2880 x 1600 (1440 x 1600 per eye).AdChoices广告Regardless of the headset you choose – if you choose one at all – you’ll be paying the same price: $399. That $400 price tag gets a Quest headset with 64GB of storage, but there is a 128GB model that runs $499 as well. Both headsets are available today from the Oculus store or from retail partners like Amazon, Best Buy, Newegg, Walmart, and GameStop. If, for instance, you’ve already got a reasonably beefy gaming PC, the Rift S might be the better the choice. The Rift S is a tethered headset, which means it needs to be connected to a PC to function, but the big difference in comparison to the original Rift is that the Rift S doesn’t need any external sensors. The Rift S is capable of “room-scale tracking with minimal setup” relying only on its own hardware and the graphics power from your PC.last_img read more

Boeing reveals 100m 737 MAX victim fund after 2018s record 101bn revenue

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first_imgToday Boeing revealed that they would provide $100 million in funds to victims of the pair of crashes of Boeing 737 aircraft in the last year. Lion Air Flight 610 and Ethiopian Airlines Flight 302 resulted in the loss of a total of 346 lives. Divided 346 ways, $100 million comes to $289,017 per person. The announcement was released today, the day before Independence Day in the USA. According to Boeing PR, “Boeing [NYSE: BA]* announced $100 million in funds to address family and community needs of those affected by the tragic accidents of Lion Air Flight 610 and Ethiopian Airlines Flight 302.”*Yes indeed, the press release for the funds pledge did include the stock ticker code for the New York Stock Exchange listing of Boeing, the publicly-traded company. This isn’t entirely strange, really – most press releases have this bit. This detail strengthens the feeling that Boeing’s handling of this situation continues to feel extremely calculated and cold.“The families and loved ones of those on board have our deepest sympathies,” said Dennis Muilenburg, Boeing chairman, president and CEO. “We hope this initial outreach can help bring them comfort.” Of note: It’s quite likely that accepting this money from Boeing will bar victims from further legal action against Boeing.Lion Air Flight 610 • Aircraft: Boeing 737 MAX 8• Time in air: 12-minutes• Fatalities: 189 human lives lostEthiopian Airlines Flight 302• Aircraft: Boeing 737 MAX 8• Time in air: 6-minutes• Fatalities: 157 human lives lostThe Boeing Company:• 4th-quarter 2018 earnings: Record revenue, $28.3 billion• Full-year 2018 earnings: Record revenue, $101.1 billion“Boeing does not understand that the families at this point in time are not interested in its money,” said Robert A. Clifford, lawyer for many families affected by the crash of the Boeing 737 Max8 aircraft in Ethiopia.“The fact is that what is foremost on the minds of these families is getting back the human remains from the crash site,” said Clifford. “To date that process has been torturously slow without a great deal of communication from Ethiopia. If Boeing really wanted to help, it would take all that money and devote it to accelerating the remains recovery/identification process for these families.” Story TimelineAll Boeing 737 Max flights suspended in Europe, but not USA (yet)Boeing 737 MAX close to returning to service insists companyAnother Boeing 737 MAX flaw tipped to delay upcoming test flightlast_img read more

2020 Toyota Prius Prime gains a 5th seat and more

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first_imgToyota says that the Prime name in the model is fitting as this is the most technologically advanced Prius in the model’s nearly two-decade history. The 2020 Prius Prime can run in either EV or hybrid driving modes and has several new upgrades for the 2020 model year.One of the significant upgrades is the addition of a fifth seat in the back for more room and people-hauling capability. The car can now seat three people in the back. Toyota added standard Apple CarPlay, SiriusXM, and Amazon Alexa compatibility. Toyota gave the 2020 Prius two more 2.1A USB ports for rear passengers to keep devices charged up and running. For more driver comfort, a new sun visor extender helps to keep the Sun out of your eyes. Buttons for controlling the seat heater have been relocated for ease of use.AdChoices广告Prius Prime is the most efficient Toyota hybrid so far. The vehicle has an EPA-estimated 54 mpg combined fuel rating and a 640-mile total driving range. The Prius can drive for 25-miles in EV mode using electricity alone. Toyota notes that the Prius Prime is HOV-approved as a single occupant green vehicle in California and New Jersey. Toyota is talking up the 2020 Toyota Prius Prime and billing the hybrid as an answer to rising fuel prices. The new ride will hit dealers this summer, and the LE grade will start at $27,600, the mid-range XLE grade will start at $29,500, and the Limited grade will be $33,500.last_img read more

State Highlights Health Care Homes Show Promise In Minn Texas Womens Health

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first_img This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. A selection of health policy stories from Minnesota, Texas, Louisiana, Florida, New York and Massachusetts.Minnesota Public Radio: Study: Program Focused On Preventive Medicine, Team Treatment Shows Promise?A health care effort focused on preventive medicine and a team approach to treatment is showing promise improving care and reducing costs, state officials say. The Health Care Homes initiative has increased patient access to clinics, particularly for people of color, while improving quality and coordination of care, according to a state study released Thursday. Health Care Homes is not home health care. The idea is to change the way clinics provide care from a traditional, illness-based model, to one that strives to improve the health of patients with chronic conditions and disabilities (Benson, 2/20).The Star Tribune: Minnesota’s New Way Of Seeing Patients Has Improved Health Care Results, Researchers SayA new model of primary care that emphasizes disease prevention and doctor-patient collaboration appears to be lowering Minnesota’s medical costs while raising the quality of care patients receive. Patients seen at “health care homes,” created as part of far-reaching state health reforms enacted in 2008, had medical costs that were 9 percent less between 2010 and 2012 than those for patients who sought primary care at traditional clinics, according to a set of reports released Thursday by the University of Minnesota and the state Health and Human Services departments. Those patients also received more effective care for asthma, vascular disease and other chronic conditions, the researchers found (Olson, 2/20).The Associated Press/Washington Post: Group Sues To Force Insurers To Take AIDS MoneyAn advocacy group has filed a federal lawsuit seeking to force insurance companies in Louisiana to take payments from a federal program that helps HIV and AIDS patients. Lambda Legal filed the suit in a Baton Rouge federal court Thursday saying at least one insurance company is violating the Affordable Care Act by refusing to take premium payments from the federal Ryan White HIV/AIDS program (2/20).The Dallas Morning News: Texas Women’s Health Program Adds Providers, But Fewer Sign UpState officials told lawmakers Thursday that the state has lined up providers and has the capacity to serve more poor women in the Texas Women’s Health Program, but fewer women have signed up for the help. The state’s family planning programs have been the subject of fights over budget cuts and abortion issues in recent years, with cuts to Planned Parenthood, a drop of millions in federal funding and then an infusion of state money. Now, as the dust settles, state officials told the Senate Committee on Health and Human Services that the new programs will be able to provide more poor women with family planning services than before (Martin, 2/20).Miami Herald: Health Care’s Hidden Costs Can Take Patients By SurpriseWhen a rheumatologist told Linda Drake of Miami that she might have lung cancer, the former smoker did some research and discovered a study for early detection and treatment of the disease with researchers in South Florida. Drake, 57, decided to participate in the study because there was a $350 flat fee, and she could enroll through UHealth — the University of Miami’s network of clinics and hospitals … The results were negative. Drake breathed a sigh of relief. But a few days later, an unpleasant surprise arrived in the mail: a bill for $210 from UHealth for “hospital services” labeled as “Room and Board – All Inclusive,’’ even though she never set foot in a hospital or spent the night at the clinic (Chang, 2/20).The New York Times: A Pharmacy Provides Salves For A Community’s SpiritsJust about no one knows the territory like a neighborhood pharmacist, membrane by membrane. On Jan. 3, 2012, Dichter Pharmacy in the Inwood section of upstate Manhattan burned to the ground along with the entire corner of 207th Street and Broadway. Under one flag or another, a drugstore had been in roughly that spot for 90 years, but this certainly seemed like the end (Dwyer, 2/20).WBUR: A New Demand For Mass. Health Mergers: Show Proof Of SavingsWhat seemed like a routine meeting of a state commission in the basement of Boston’s beautiful main public library may become a milestone for health care reform in Massachusetts. It could be the “Show Me The Money” moment for health care cost control. From here on out, hospitals, physician groups and other providers proposing to merge will have to show the state’s Health Policy Commission (HPC) that the newly formed entity would save money and that those savings would be passed along to consumers (Bebinger, 2/20).Minnesota Public Radio: Report: Prison Health Care System Needs More AccountabilityA new report concludes health care services provided to the roughly 9,000 adult inmates in Minnesota prisons should be better coordinated and accountable. Perhaps because of snow-slopped roads, the official release today of the report from Minnesota Legislative Auditor Jim Nobles drew only a sparse crowd. Only three of the 12 lawmakers who typically review legislative-auditor reports attended the hearing. Nobles said he understands that the topic of prison health lacks a natural constituency (Yuen, 2/20). State Highlights: ‘Health Care Homes’ Show Promise In Minn.; Texas Women’s Health Providers; Fla.’s Hidden Costslast_img read more

Work On StateRun Obamacare Exchanges Not Done Government Watchdog Says

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first_img Elsewhere, an Oregon lawmaker wants to ban transgender teens from having reassignment surgery without parental consent. And Government Executive and The Wall Street Journal look at how many uninsured remain – A new state audit takes issue with how MassHealth, the state’s health insurance for low-income residents, spent $4 million, WBUR reports. State Auditor Suzanne Bump says she found problems with how payments for wheelchairs and wheelchair parts were authorized. “We found that there were not proper authorizations for claims, we also found that nursing homes had submitted duplicative bills,” she said in an interview. (9/17) Among U.S. states, Texas had the highest percentage and greatest number of people without health insurance coverage in 2014, according to new U.S. Census Bureau data released on Wednesday. Of the roughly 25.9 million people in the Lone Star State, 19.1 percent, or just over 5 million, lacked health insurance last year, according to Census Bureau estimates. … The map [with this post] shows some of the data the Census Bureau published for each state. (Lucia, 9/16) The Oregonian: Oregon Lawmaker Wants To Bar Transgender Teenagers From Sex Reassignment Surgery Without Parents’ Permission More than a year after launching, state-run health insurance exchanges, including Connecticut’s, still hadn’t fully completed key information technology functions, federal auditors said in a report released Wednesday. The Government Accountability Office’s report, which noted that states have spent close to $1.45 billion in federal funds on IT systems for the insurance marketplaces created by the federal health law, rated the 14 state-run exchanges’ capabilities as of February in four categories. (Levin Becker, 9/17) Work On State-Run Obamacare Exchanges Not Done, Government Watchdog Says And states have already spent close to $1.5 billion on IT systems for the marketplaces. Elsewhere, Alaska lawmakers hire a lawyer to challenge the proposed Medicaid expansion there, an audit of Massachusetts’ low-income health insurance program finds spending problems and health coverage costs there fail to stay flat despite officials’ efforts. WBUR: As State Agency Fails To Keep Premiums Flat, What’s Ahead For Cost Control In Mass. There’s a growing list of warning signs that Massachusetts, despite lots of effort, may be losing the battle to control health care costs. Last month, the Division of Insurance approved a 6.3 percent increase in the base rate for small businesses. Then, we heard that Massachusetts came in over the target cap for health care spending last year. And now, an attempt to keep health care premiums flat for the largest employee group in the state has failed. (Bebinger, 9/17) Government Executive’s Route Fifty: Stats Shot: Which States Have the Most Residents Without Health Insurance? An Oregon legislator wants lawmakers to bar 15-year-olds from using the Oregon Health Plan to pay for sex reassignment surgery. No minors have yet used the state insurance to pay for such a surgery. But Carl Wilson, R-Grants Pass, said a 2014 decision to offer Oregon Health Plan coverage for transgender-related medicines and procedures could allow teenagers to make life-altering decisions they will later regret. (Parks, 9/17) Alaska Dispatch News: Legislature Hires Attorneys To Challenge Medicaid Expansion The Alaska Legislature has signed a contract for lawyers to take on Gov. Bill Walker’s expansion of Medicaid, drawing criticism from some of its own members who had urged them to not continue after an early loss. The contracts signed Tuesday for up to $450,000 include a signing bonus of $100,000, said Sen. Berta Gardner, D-Anchorage. … The Legislative Council, the Legislature’s operating arm, decided in August to sue Walker and his commissioner of Health and Social Services, Val Davidson, to block expansion, but failed to get an injunction before the state began enrolling Alaskans in the program on Sept. 1. (Forgey, 9/17) WBUR: Audit Of MassHealth Finds Problems With $4M In Spending The Wall Street Journal’s Real Time Economics: More Americans Have Health Insurance. Here’s Who Still Doesn’t The Connecticut Mirror: GAO: Still Work To Do On Obamacare State Exchange IT Systems The share of Americans without health insurance has plunged, but significant demographic gaps remain between who has coverage and who does not. The Census Bureau reported Wednesday that men, particularly young men, are much more likely to be uninsured than women. (Zumbrun and Overberg, 9/17) This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.last_img read more

The Government Should Get Into The GenericDrug Making Business To Curb High

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first_img Sen. Elizabeth Warren (D-Mass.), a likely 2020 presidential candidate, will release a bill on Tuesday that would effectively create a government-run pharmaceutical manufacturer to mass-produce generic drugs and bring down prices, several sources in her office told POLITICO on Monday in an exclusive preview of the legislation. The bill, dubbed the Affordable Drug Manufacturing Act, is unlikely to pass the Republican-led Senate, but it signals that a future Warren White House could try to radically revamp the federal government’s role in the pharmaceutical market in order try to lower prices. (Thompson and Karlin-Smith, 12/17) Want more information on lawmakers’ ties to pharma? Explore our Pharma Cash To Congress database. While South Carolina’s longest-serving congressman threw his support to research and the growth of the multibillion-dollar pharmaceutical industry in his district, drug- and device-making companies rewarded him by giving liberally to his campaign war chest for years. U.S. Rep. Jim Clyburn, D-Columbia, has collected more in the last decade from powerful political action committees attached to the pharmaceutical industry than anyone else in the House or Senate, according to Kaiser Health News and a Post and Courier analysis. (Wildeman, 12/16) NPR: Sen. Cory Booker Seeks Increased Transparency In Medicaid’s Drug Decisions Sen. Cory Booker, D-N.J., says he will introduce federal legislation this week that would require more transparency surrounding states’ Medicaid drug decisions. The bill comes in response to a recent investigation by the Center for Public Integrity and NPR. The measure, known as the “Medicaid Drug Decisions Transparency Act,” would require pharmaceutical companies to disclose their payments to pharmacists and others who serve on state Medicaid drug boards. These boards help decide which drugs Medicaid patients will be able to access easily. Currently drugmakers must only disclose perks given to doctors, such as free dinners, speaking fees and consulting gigs. In addition, the bill would increase penalties for companies that fail to comply with reporting requirements. (Whyte, 12/17) The Post and Courier: Clyburn Has Taken More Than $1 Million In Pharma Money In A Decade, Far Surpassing Peers center_img The Government Should Get Into The Generic-Drug Making Business To Curb High Prices, Sen. Warren Says Democratic Sen. Elizabeth Warren’s bill would establish an Office of Drug Manufacturing that would be required to manufacture at least 15 different generic drugs in its first year where the agency determines there is a failure in the market. Meanwhile, Sen. Cory Booker (D-N.J.) is also introducing legislation geared toward high drug costs and increasing transparency in Medicaid funding. This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. And, in other news — Politico: Warren Bill Would Get Feds Into Generic Drug Manufacturing last_img read more

Amazons new Fire 7 tablet gets you handsfree Alexa for a bargain

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first_img This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Amazon has just announced the latest version of its affordable Fire 7 tablet and it brings a few key upgrades to the party.Before we get onto specs or features, it’s important to note this is a super-cheap tablet. At £49.99 it severely undercuts just about everything else out there.The biggest update this year is a feature that has become commonplace among Fire tablets: hands-free Alexa. You can ask Amazon’s handy voice assistant to play music, set timers or control lights and unlike previous Fire 7’s you don’t need to hit a button to initiate this.There’s a faster processor inside the Fire 7 this time too. While it doesn’t give specifics, Amazon states it’s a 1.3Ghz processor. It has also doubled the base storage from 8 to 16GB. Pay a bit more and you can double that again to 32GB. There’s a microSD slot too which can handles cards up to 512GB.Related: Best tabletsAmazon’s Fire tablets have great integration with the brand’s Prime Video service, along with Kindle books and Audible audiobooks. If you’re deep in the Amazon ecosystem then you’ll find all that content front and centre when you boot up the device.Other features include a 7-inch IPS display, a durable body and a camera on both the front and back. It’s all basic stuff but for the price it’s hard to complain.A nice touch is a trio of new colours, which replace the slightly luridly bright hues from before. There’s Twilight Blue, Plum and Sage. Oh, there’s a standard black option too.If you’re keen on the new Fire 7 you can pre-order it today from Amazon.co.uk, with devices beginning to ship on June 6. There’s a selection of cases available too with a price of £24.99. Once it goes on sale you’ll be able to pick it up from stores like Tesco and John Lewis & Partners. Show More Unlike other sites, we thoroughly review everything we recommend, using industry standard tests to evaluate products. We’ll always tell you what we find. We may get a commission if you buy via our price links.Tell us what you think – email the Editor Sign up for the Mobile NewsletterSign Up Please keep me up to date with special offers and news from Goodtoknow and other brands operated by TI Media Limited via email. You can unsubscribe at any time. We’d also like to send you special offers and news just by email from other carefully selected companies we think you might like. Your personal details will not be shared with those companies – we send the emails and you can unsubscribe at any time. Please tick here if you are happy to receive these messages.By submitting your information, you agree to the Terms & Conditions and Privacy & Cookies Policy.last_img read more

5 Things To Know About The 2018 Toyota Sienna Minivan

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first_imgKeep everyone app-happyI can’t gush enough about the dual power sliding side doors and power lift gate. Both offered a satisfying relief when I had a handful of groceries or luggage to load. Then there were the times we needed to whisk a couple visiting toddlers into the rear seats and place the little ones in their car seats.(5) Kid FriendlyIf I didn’t know better, I would think Toyota invited some kids to work with their interior product design group. For starters, the 2018 Sienna offers a rear-seat entertainment system, a feature not available on some competitive minivans. The system in the Sienna includes wireless headphones, so up-front passengers can listen to each other, and a screen that divides in half so back-seaters can play a game on one side and watch a movie on the other.And then there’s the rear seat climate control. Many drivers prefer a cooler cabin, but that might not be amenable to kids or adult passengers in the back. With the Sienna’s rear climate controls, rear passengers can be as warm as they like while the driver stays cool and alert.A functional family vehicle needs this kind of spaceThe Sienna’s Driver Easy Speak feature is more for mom and dad than for the kids. Minivans have gigantic cabins, and it can be difficult making yourself heard if you have kids seated in the third row. This amenity is essentially an in-vehicle public address system. It provides a microphone that allows you to transmit your voice via the rear speakers. It’s an essential tool for civilized family communication.Related Stories You Might Enjoy—Other Minivan ChoicesRoad Test: 2018 Chrysler Pacifica HybridRoad Test: 2014 Honda OdysseyDisclosure:Clean Fleet Report is loaned free test vehicles from automakers to evaluate, typically for a week at a time. Our road tests are based on this one-week drive of a new vehicle. Because of this we don’t address issues such as long-term reliability or total cost of ownership. In addition, we are often invited to manufacturer events highlighting new vehicles or technology. As part of these events we may be offered free transportation, lodging or meals. We do our best to present our unvarnished evaluations of vehicles and news irrespective of these inducements.Our focus is on vehicles that offer the best fuel economy in their class, which leads us to emphasize electric cars, plug-in hybrids, hybrids and diesels. We also feature those efficient gas-powered vehicles that are among the top mpg vehicles in their class. In addition, we aim to offer reviews and news on advanced technology and the alternative fuel vehicle market. We welcome any feedback from vehicle owners and are dedicated to providing a forum for alternative viewpoints. Please let us know your views at publisher@cleanfleetreport.com. Source: Electric, Hybrid, Clean Diesel & High-MPG Vehicles Road Test of a Stalwart with Exclusive FeaturesOnce the favorite choice for families across the nation, the minivan has fallen out of fashion these days. And that’s a pity, because they’re probably the most practical vehicle ever invented. When it comes to moving people and things, it’s hard to beat the utility of a big, rectangular box on wheels. (Full disclosure: We’ve been minivan owners for 20 years. Ed note: We’re a little late in publishing this review since the 2019 models are on the lot now; the good news is there are so few changes that Toyota hasn’t even published a press kit for the 2019 Sienna.)Sales are down overall, but the minivan segment still has a lot to offerToyota introduced the Sienna minivan in 1997. It was on the small side compared to other offerings. Over the years it has grown in size and power to match or exceed its competitors. Until last year, the Sienna topped the minivan sales chart, but remains a solid choice, especially when it comes to standard safety features.What’s New For 2018?For the 2018 model year, Toyota has given the Sienna a refresh designed to brighten its luster. All trim levels—L, LE, SE, XLE and Limited—have a redesigned front fascia and a larger, lower grill and side lower rockers. Want to block out road noise? The SE grade for the 2018 Sienna now includes a laminated front windshield, while the Limited grade has acoustic front row side glass as well.Tech upgrades are visible on the displaySafety is an important criterion with any vehicle choice, and the 2018 Sienna stands above the minivan crowd. Standard on all models is Toyota’s TSS-P system, a multi-feature advanced safety suite. Included in the TSS-P is: A pre-collision system with pedestrian detection, full speed range dynamic radar cruise control, lane departure alert with steering assist and automatic high beams. A blind-spot monitor and rear cross-traffic alert are offered as optional equipment.Toyota has also equipped all 2018 Sienna models with the new Entune 3.0 infotainment system. The Sienna L, LE, SE and XLE grades will have the Entune 3.0 system with navigation and App Suite Connect. Moving to the LE, SE, and XLE grades will give you the Entune Audio Plus, which includes things like Safety Connect and Wi-Fi Connect for up to five mobile devices. There are also five USB ports through the three rows.After spending a very pleasant week with the 2018 Sienna, here are the five things you should know about this minivan.(1) Seats Up To Eight, BIG Cargo Space, Smooth RideThe chief reason for buying a minivan is seating. The 2018 Sienna’s seven-passenger configuration puts a pair of tip-and-slide captain’s chairs in the second row and a bench seat in the third row. The LE and XLE trims can be ordered with a second-row bench seat that brings its seating total to eight.It’s all about spaceAnother reason is cargo capacity. These vehicles are built to provide cavernous capacity for your family’s gear and large bulky items. The Sienna provides 39.1 cubic feet of cargo space with the third row in place, more than any other minivan. The third-row seats quickly stow into the floor and that opens up 87.1 cubic feet. But to achieve the maximum 150-cubic-foot cargo capacity, you have to remove the bulky second-row seats.Fully loaded with people and things or just the driver, the 2018 Sienna provides a smooth ride. It easily travels over road imperfections without jostling passengers. As an added note, if you are cross-shopping the Sienna with crossovers, check out forward visibility–the Sienna has a tall greenhouse that provides superb sight lines in most directions.(2) Responsive V6 EngineThe 2018 Sienna’s 3.5-liter V6 engine sends 296 horsepower and 263 pounds-feet of torque to the front wheels. It has the resources to provide the Sienna with the muscle it needs to deliver reasonably eager response to throttle inputs. Thanks to the engine’s nearly 300 horses, the Sienna shines when it comes to acceleration. Even with that much power, the Sienna returns Excellent fuel economy—19 mpg city/27 highway/22 combined.The engine is connected to an eight-speed automatic transmission with the ability to select gears. This is helpful when tackling a long grade in a loaded vehicle that’s going uphill or downhill. Doing this is easy—just move the gear lever all the way down and to the left to select gears on your own.(3) Exclusive All-Wheel Drive AvailableAll the wheels on the minivan are powered to go ’roundAttention snow belt minivan buyers! Sending power to all four wheels rather than just the front two is a huge help when you’re struggling for traction in snow and ice. The 2018 Toyota Sienna is the only minivan that offers all-wheel drive (AWD). For that reason alone, the AWD should definitely be one of your “must have” features. (ed. note: You will lose a few mpg that way; the AWD clocks in at 18/24/20).(4) Loads Of FeaturesIn addition to the above standard safety and infotainment features, the 2018 Sienna has loads of features. Even the base model comes standard with cruise control, tri-zone climate control, rearview camera, automatic headlights, 6.1-inch touch screen, AM/FM/CD player with USB, and iPod and Bluetooth connectivity with Siri Eyes Free for Apple devices. Moving up the lineup brings power-adjustable driver’s and front passenger’s seat, roof rack, leatherette or genuine leather seats, push-button start, moonroof and, my favorite feature, a 360-degree surround-view monitor.High-tech features fill the dashlast_img read more

Mortara Fourth Place At Santiago Formula E Race Was Like A Win

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first_imgEdoardo Mortara says his fourth-place finish in the Santiago ABB FIA Formula E race was “like a victory” for his Venturi team after a difficult start to the 2018/19 season. Mortara took fourth after BMW Andretti driver Alexander Sims was given a post-race penalty for tapping him into a spin.The Venturi racer had to hold off fierce attention from Virgin Racing’s Robin Frijns and Jaguar driver Mitch Evans after his incident with Sims, but held on to secure his team’s first points of the season.More Formula E News Source: Electric Vehicle News The Technology Gains That Have Transformed Formula E “It’s like a victory for us, to be honest,” Mortara told Motorsport.com. “We had very difficult weekends in Riyadh [Ad Diriyah] and Marrakech.“We managed to extract pretty much the entire potential of the car and probably even more.“It was definitely not easy and we had to overcome a lot of issues but at least we take the points, this fourth place is a boost, a motivation for everyone in Venturi. It was definitely not easy [in the heat].“We had to manage things and at the moment with the tools that we have in the car for the engineers we can’t really predict as well as the others what is going to happen with the temperature of the battery, the energy and all this stuff.“It was definitely more difficult for us than for the others, but I’m happy that we overcame these issues. It’s one of the longest races I ever had.”Mortara’s fourth place in Santiago comes after two disappointing opening race weekends for Venturi.At the season opener, Mortara was hampered by braking issues, while teammate Felipe Massa lost a likely points finish due to a series of penalties.Both drivers finished the Marrakech race but were 13th and 18th, with Mortara ahead of Massa.Speaking before the race in Santiago, Venturi team principal Susie Wolff said the technical challenges her squad has faced so far this season cannot be traced to one issue in particular.“It’s not one main area,” Wolff told Motorsport.com. “In the end, it’s a number of small issues that we’ve got to get sorted on the reliability front and the performance front.“One of the issues is with the powertrain, but like we also saw in Riyadh especially, we’ve also got issues with the braking, and all of it, in a roundabout way, is connected.“It’s just [about] progressing one step at a time and making sure that each issue gets sorted and then the next one.“It was always going to be a challenge because we had issues in testing – we started testing late.“We at least know what know what the problems are and are managing to face them head on and sort them out.”center_img Why Santiago Will Be Toughest Test For Formula E Gen 2 Cars Audi Gains More Knowledge From Formula E Than F1 Author Liberty Access TechnologiesPosted on February 1, 2019Categories Electric Vehicle Newslast_img read more

Rivian R1T EV Pickup Truck Range Exceeds 400 Miles Heres How

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first_imgSource: Rivian Forums Author Liberty Access TechnologiesPosted on February 21, 2019Categories Electric Vehicle News Rivian Pricing: Think GMC Denali, Chevy Suburban, Loaded Ford F-150 See Rivian R1T Pickup Truck & R1S Electric SUV Side-By-Side Source: Electric Vehicle News Rivian R1T Specs, Features & More Highlighted In New Video The electric pickup truck has a patented add-on battery that extends range beyond 400 miles. And here we thought 400 miles was already way more than enough.Have a look at the patent image below. We’ve included the title and abstract too:Electric Vehicle With Modular Removable Auxiliary Battery With Integrated CoolingAbstractAn electric vehicle system for transporting human passengers or cargo includes an electric vehicle that includes a body, a plurality of wheels, a cargo area, an electric motor for propelling the electric vehicle, and a primary battery for providing electrical power to the electric motor for propelling the electric vehicle. An auxiliary battery module is attachable to the electric vehicle for providing electrical power to the electric motor via a first electrical connector at the auxiliary battery module and a second electrical connector at the electric vehicle that mates with the first electrical connector. The auxiliary battery module can be positioned in the cargo area while supplying power to the electric motor, and can be removable and reattachable from the electric vehicle. The auxiliary battery module includes an integrated cooling system for cooling itself during operation of the electric vehicle including a conduit therein for circulating coolant. It seems the Rivian range-extending pack (officially called the Auxiliary Battery Module) bolts into the bed of the pickup truck and can be connected/activated when needed.The idea is okay, but in reality, that battery is going to cost quite a bit and it surely won’t be light.Rivian Forums adds:The battery is removable and reattachable to the vehicle, supplying power to the electric motor by being positioned in the cargo area (i.e. the cargo bed of the R1T). Once attached, the vehicle can automatically detect the battery module and make necessary adjustments according to a set of multiple predetermined features sets that determine driving performance, suspension characteristics, braking performance/sensitivity, steering ratio, etc.Here’s the initial spec sheet for the Rivian R1T. Note that the removeable battery pack would extend the range of all versions, but only the top-line R1T would exceed 400 miles with this added pack. By exactly how much though is still unknown: Range of over 400 miles?Yes, that’s right.Rivian was holding back on a little range-extending secret for its R1T electric truck, but now we know what’s coming.More Rivian Truck Newslast_img read more

Aston Martin Rapide E Debuts At 2019 Shanghai Auto Show Video

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first_img Aston Martin Rapide E Validation Prototype Moves Under Own Power Press blast:PRODUCTION READY RAPIDE E GIVEN WORLD DEBUT AT AUTO SHANGHAI· Aston Martin’s first electric model – Rapide E – now ready for production· Car unveiled at Auto Shanghai by Aston Martin Chief Creative Officer, Marek Reichman· Rapide E features 800V battery system for greater charging efficiencies· Twin rear-mounted motors produce 610PS and 950Nm of torque· Production limited to 155 examples· Visit Aston Martin’s stand – Hall 8 Stand 8A3116 April 2019, Shanghai, China: Aston Martin Lagonda has revealed the final production-ready iteration of its first all-electric production car, with the spectacular Rapide E making its world debut at China’s Auto Shanghai motor show.Unveiled by Aston Martin Executive Vice President & Chief Creative Officer, Marek Reichman, Rapide E is a pivotal model for the luxury marque. Following the success of previous special-edition models, including Aston Martin Vulcan, the Vanquish Zagato family and DB4 GT Continuation, Rapide E continues to deliver a superior level of performance, craftmanship and exclusivity, while also propelling Aston Martin into the all-electric realm.The first car to be built at Aston Martin’s state-of-the-art St Athan production facility – the brand’s Home of Electrification – Rapide E represents a pioneering first step towards achieving the company’s wider electrification strategy and the successful fruition of Lagonda – the world’s first zero-emission luxury brand. A special edition with a production run strictly limited to 155 units, Rapide E has been developed in collaboration with Williams Advanced Engineering (WAE).Shown for the first time here in Shanghai today, Aston Martin’s design and engineering teams have worked in partnership to extract the optimal aerodynamic performance available from the Rapide’s elegant form. Traditional metal vanes give way to a striking honeycomb front grille. With lower cooling requirements demanded of the EV powertrain, Aston Martin’s aerodynamic engineers have been given the freedom to optimize the aperture of the frontal area, minimising airflow through the car’s body, improving the car’s aerodynamic efficiency and increasing range as a result.A re-designed underfloor streamlines airflow from the front splitter right the way through to Rapide E’s new larger rear diffuser – a feature that is now wholly dedicated to aero efficiency due to the removal of the exhaust system required before. The model’s forged aluminium aerodynamic wheels – shod with bespoke low rolling-resistance Pirelli P-Zero tyres – have also been re-designed to give greater efficiency, without compromising brake cooling capability. The sum of these changes gives Rapide E’s aerodynamic package an 8% improvement over the previous internal combustion model.Inside and out, Rapide E is equipped with the materials and technology befitting of the marque’s first EV model. Gone are the analogue displays of the past. A 10” digital display now sits in their place, delivering all key information to the driver while on the move, including the battery’s state of charge, current motor power levels, regenerative performance and a real-time energy consumption meter. Swathes of carbon fibre have been deployed throughout, assisting in delivering the strict weight targets set by Aston Martin’s engineering team from the outset.Extending the experience beyond the car, a dedicated app allows key information from the car to be remotely monitored. This powerful dashboard displays remaining range, battery status, and time to charge, as well as allowing navigation destinations to be sent from the app to the car for easy route planning. The car’s parking spot can also be seen via the app, with walking directions provided to help re-locate it in busy locations. Finally, the health and status of Rapide E can also be tracked from the app, providing reminders such as when a key service is due.Throughout the development process, the combined AML/WAE engineering team first focussed their efforts on finding packaging solutions for the battery system and motors within the Rapide’s architecture before working to achieve effective cooling of the batteries and motors.Rapide E is powered by an 800V electrical architecture battery – encased in carbon fibre and Kevlar casing – with a 65kWh installed capacity using over 5600 lithium-ion 18650 format cylindrical cells. This bespoke battery pack lies where the original 6.0-litre V12, gearbox and fuel tank were located, with the 800V system allowing for more efficient charging and greatly improved thermal characteristics over existing electrical architectures. This battery system powers two rear mounted electric motors producing a combined target output of just over 610PS and a colossal 950Nm of torque.Rapide E’s range is over 200 miles under the Worldwide Harmonised Light Vehicle Test Procedure (WLTP), while the model is capable of charging at a rate of 185 1,2 miles of range per hour using a typical 400V 50kW charger. However, the car’s 800V high-voltage battery system enables faster charging of 310 1,2 miles of range per hour, using an 800V outlet delivering 100kW or higher. For destination charging, the car also features an industry-leading high-power AC on-board charger capable of recharging the battery in as little as 3 hours.Top speed for Rapide E is 155mph, with a sub-4.0 second 0-60mph time and a 50-70mph time of just 1.5 seconds. These figures are not restricted to a narrow window of battery charge or climatic conditions, instead, thanks to the cutting-edge 800V architecture, the Rapide E will deliver its performance in a consistent and repeatable way as would be expected from a traditional Aston Martin product. This includes the ability to drive a full lap of the Nürburgring with no performance derating of the battery or the motors.Rapide E also enhances the feel, character and delivery of the V12-engined recently acclaimed Rapide AMR, thanks to careful attention paid to the tuning of both the electric powertrain and the chassis across three driving modes – GT, Sport and Sport + – which are selected for both the powertrain and handling. The rear-wheel drive Rapide E’s twin electric motors drive through a Limited-Slip Differential, which combined with a revised spring and damper rates, ensures the pure handling characteristics of the petrol-powered Rapide AMR are retained.Speaking ahead of Rapide E’s Shanghai debut, Dr Andy Palmer, President and Group CEO, Aston Martin Lagonda, commented: “Unveiling the Rapide E will be a huge moment for Aston Martin. As our first all-electric production car, it is a truly historic step. One that signals Aston Martin is prepared for the huge challenge of an environmentally responsible and sustainable future. As a car company we cannot afford to passively allow that future to come to us; we have to actively chase it. Only by doing this can we learn and prepare, but also preserve those things we love as drivers and car enthusiasts. That’s why it was so important to me that in embracing EV technology we should not let go of those unique qualities that define an Aston Martin. I believe Rapide E embodies that desire and paves the way for a hugely exciting future.” Aston Martin Reveals Secrets Of Rapide E: Range Over 200 Miles In terms of specifications, there is no changes to the preliminary one from fall 2018. Aston Martin uses a 65 kWh battery system (800 V nominal), which should be good for over 200 miles (320 km) under the WLTP test cycle. We feel that the battery capacity should be higher, especially if customers would like to make use of the strong acceleration from 0-60 mph in less than 4 seconds. The 200 miles sounds like a minimum for such a type of car in 2019, and 250-300 miles would be more appropriate. Anyways, interestingly the packs will consist of 18650 format cylindrical cells.“Rapide E is powered by an 800V electrical architecture battery – encased in carbon fibre and Kevlar casing – with a 65kWh installed capacity using over 5600 lithium-ion 18650 format cylindrical cells. This bespoke battery pack lies where the original 6.0-litre V12, gearbox and fuel tank were located, with the 800V system allowing for more efficient charging and greatly improved thermal characteristics over existing electrical architectures. This battery system powers two rear mounted electric motors producing a combined target output of just over 610PS and a colossal 950Nm of torque.”The battery can be recharged at up to around 100 kW of power. The on-board charger seems to be three-phase 22 kW as it can replenish full range in three hours.Aston Martin encourages that the battery will be able to withstand prolonged drive at high power, like a full lap of the Nürburgring without entering limited power mode. This is probably where Williams Advanced Engineering’s experience in Formula E counts the most.“These figures are not restricted to a narrow window of battery charge or climatic conditions, instead, thanks to the cutting-edge 800V architecture, the Rapide E will deliver its performance in a consistent and repeatable way as would be expected from a traditional Aston Martin product. This includes the ability to drive a full lap of the Nürburgring with no performance derating of the battery or the motors.”.embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; }Aston Martin Rapide E specs:range of more than 200 miles (320 km) under WLTP cycle65 kWh battery (5,600 lithium-ion cells – 18650 type)rear-wheel drive with two motorstotal system output of 610 PS and 950 Nm0-60 mph (nearly 100 km/h) in less than 4 seconds50-70 mph in 1.5 secondstop speed of 155 mph (250 km/h)800 V system voltage with capability to charge at 100 kW or more3 h recharge using on-board charger 11 photos Aston Martin Shows Off Battery For Upcoming Rapide E Only 155 to be made with a range of over 200 miles (320 km)Aston Martin unveiled at the 2019 Shanghai Auto Show the final production-ready iteration of the Rapide E all-electric sports saloon, developed in collaboration with Williams Advanced Engineering (WAE).According to the luxury marque, it’s a pivotal model – the first BEV, which will be produced in a limited run of 155 examples. It looks pretty cool and could become an alternative proposition for those who seek something more exotic than the Tesla Model S or Porsche Taycan, while at the same time electric.Compared to the standard Rapide with a 6.0-litre V12, the Rapide E was highly redesigned – for example, the new aerodynamic package brings 8% less drag. There is now no analogue displays and the dedicated app allows key information from the car to be remotely monitored.Aston Martin news Author Liberty Access TechnologiesPosted on April 16, 2019Categories Electric Vehicle News Source: Electric Vehicle Newslast_img read more

EGEB UK solar panel taxes Australian rooftop solar booming windbrewed beer and

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first_imgIn today’s EGEB:An upcoming VAT increase could stifle UK solar panel additions.But in Australia, homes and businesses keep adding more solar power.A look at Budweiser’s wind power deal.Very few ships are large enough to carry offshore wind turbine parts. more…Subscribe to Electrek on YouTube for exclusive videos and subscribe to the podcast.https://www.youtube.com/watch?v=KqMH4mh99DcThe post EGEB: UK solar panel taxes, Australian rooftop solar booming, wind-brewed beer, and more appeared first on Electrek. Source: Charge Forwardlast_img

BMW shows no desire to make own batteries in electric push frustrating

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first_imgSource: Charge Forward BMW made a number of electric vehicle announcements on Tuesday as the carmaker looks to accelerate its EV plans. But those plans still don’t involve making their own batteries, much to the chagrin of German government officials. more…Subscribe to Electrek on YouTube for exclusive videos and subscribe to the podcast.https://www.youtube.com/watch?v=V1zk7Eb8r-s&list=PL_Qf0A10763mA7Byw9ncZqxjke6Gjz0MtThe post BMW shows no desire to make own batteries in electric push, frustrating German govt appeared first on Electrek.last_img

Greenberg Traurigs Daniel Novakov Named Father of the Year

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first_img Remember me Not a subscriber? Sign up for The Texas Lawbook. Lost your password? Usernamecenter_img Password © 2014 The Texas Lawbook.By Brooks IgoStaff Writer for The Texas Lawbook(June 5) – The 2014 Father of the Year Committee named Greenberg Traurig shareholder Daniel Novakov among the three winners of DFW’s top dad award this year, the firm announced recently. Novakov, an expert on tax-related matters, was recognized with Dallas Mayor Mike Rawlings and Baylor Scott & White Health CEO Joel Allison at a luncheon at the Frontiers of Flight Museum on May . . .You must be a subscriber to The Texas Lawbook to access this content.last_img

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

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first_imgAbstract number 133: Dose dependent exogenous regulation of membrane bound Interleukin-15-Interleukin-15 receptor alpha fusion protein for adoptive T-cell therapyPresenter: Christopher ReardonSession: Cancer – Targeted Gene & Cell Therapy I Construction of a single-chain regulated IL12 using a DD derived from FKBP Demonstration of small molecule-regulated expression of IL12 in a variety of cell types including primary human T cells Use of different promoters to tune expression level of the regulated cytokine Demonstration of in vivo regulation of IL12 in adoptively transferred T cells Development of a CD19 CAR construct co-expressing regulated IL12, with in vitro data showing effective performance of the regulated cytokine cassette Source: http://obsidiantx.com/news/ Design of regulated membrane-bound IL15-IL15 Receptor Alpha (mbIL15) fusion construct incorporating DDs for pharmacologic control with small molecule ligands Construction of mbIL15-DD construct incorporating human DDs, regulated by FDA-approved small-molecule drugs Dose- and time-dependent regulation of mbIL15 expression in multiple cell types Regulation of mbIL15 expression on primary human T cells in vivo May 17 2018Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.Obsidian is developing CAR-T therapies that incorporate Destabilizing Domains (DDs) to regulate expression of immune cytokines, thereby providing pharmacologic control over these potent but potentially toxic molecules. DDs are small, fully-human protein domains that confer conditional stability to a fused payload protein that is engineered into a cell or gene therapy product. IL12 and IL15 are two important immune cytokines that play important roles in tumor response to adoptive cell therapy but which require precise control to optimize their therapeutic benefit.”IL12 and IL15 are critical factors that promote CAR-T cell expansion, persistence, and penetration into solid tumors,” said Vipin Suri, Ph.D., Vice President of Discovery of Obsidian. “However, unregulated expression of these cytokines by CAR-T or other adoptively-transferred cells can potentially compromise safety and efficacy. Obsidian’s technology allows the treating physician to control expression of IL12 and IL15 via the use of safe, FDA-approved small-molecule drugs, and the preclinical data we present today demonstrate the elegance and effectiveness of this approach.”Highlights of the two preclinical presentations follow:Related StoriesCommon cold virus strain could be a breakthrough in bladder cancer treatmentNew drug combinations and dosing schedules improve outlook in advanced colon cancerMR Solutions leads the way in developing helium free MRI systemsAbstract number 113: Exogenous In Vitro and In Vivo Regulation of Interleukin-12 Secretion from T Cells Using Destabilizing Domain TechnologyPresenter: Dexue SunSession: Cancer – Immunotherapy, Cancer Vaccines Ilast_img read more